Since 18 of December 2019 conferences.iaea.org uses Nucleus credentials. Visit our help pages for information on how to Register and Sign-in using Nucleus.

Sep 19 – 22, 2023
IAEA Headquarters
Europe/Vienna timezone
Deadline for regular contributions has passed. The system remains open for invited submissions only.

Adaptive Plasmas for Biomedical Applications

Sep 20, 2023, 9:00 AM
30m
CR-4 (IAEA Headquarters)

CR-4

IAEA Headquarters

Invited Oral Medicine Medicine

Speaker

Michael Keidar (George Washington University)

Description

The uniqueness of low-temperature plasma is in its ability to change composition in situ. Plasma self-organization could lead to formation of coherent plasma structures. These coherent structures tend to modulate plasma chemistry and composition, including reactive species, the electric field and charged particles. Formation of coherent plasma structures allows the plasma to adapt to external boundary conditions, such as different cells types and their contextual tissues. In this talk we will explore possibilities and opportunities that the adaptive plasma therapeutic system might offer. We shall define such an adaptive system as a plasma device that is able to adjust the plasma composition to obtain optimal desirable outcomes through its interaction with cells and tissues.

Various approaches for plasma therapy based on plasma adaptation to target conditions will be reviewed. These approaches are based on the ability of measuring the cellular response to plasma immediately after treatment and modifying the composition and power of plasma via a feedback mechanism. Plasma self-adaptation might be feasible due to self-organization and pattern formation when plasma interacts with targets. Plasma effect on biological targets is influenced by various factors including the plasma jet discharge voltage, gas composition, humidity and cancer cell type. To address this, we present an optimal feedback control scheme to adjust treatment conditions responsive to the biological response.

Speaker's Affiliation George Washington University
Member State or IGO/NGO United States

Primary author

Michael Keidar (George Washington University)

Presentation materials