International Symposium on Understanding the Double Burden of Malnutrition for Effective Interventions

Burden of obesity on Vitamin D status and bone health in obese Egyptian children.

Not scheduled

15m

Boardroom A (IAEA, Vienna)

Poster Biology Poster Session 4

Speaker

Prof. Moetazza Alshafei (prof. of clinical nutrition)

Description

Introduction:Children with malnutrition will have deleterious effects on their health and life either malnutrition is due decreased or increased nutrition. liability of bone health deterioration may be imminent. Aim of the study:In this study, we visualized the relation between overweightand levels ofbone deteriorationmarkers, minerals and vitamin D status in Egyptian children.Methods:40 children aged 8-13 years old were enrolled ,30 obese with body mass index (BMI) 32±2.8 and 10with BMI 24±3.1 as control group. Parathyroidhormone(PTH), Osteocalcin(OS), bone alkaline phosphatase (APH),1,25 (OH)vitaminD3(vitD3),25(OH)vitamin D3 were analyzed byimmunoradioassay kits. Serum and urinary calcium, phosphorus, hydroxy proline in urinealldone by quantitative calorimetric method.Statistical analysis:Data were expressed as mean ±standarddeviation, T Student test and Pearson correlationwere used for differences of variance.Analysis with excelfor windows 10 Microsoft was used. Results:showed high BMI group have elevation of PTH with disruption of levels of OS, APH, bone minerals, urinary hydroxyproline and vitD3 status versus control group(P≤ 0.05). Significant Positive correlation between BMI andPTH level was detected.Conclusion: Obesity positively correlated with hyperparathyroidism which can cause imminent bone mineral deterioration with liability for week bonehazards. Wide scale studies are needed, meticulous investigation of bone health in obese children as wellas calcium and vitamin D supplementation are recommended.