Thursday morning - Poster Presentations - Screen5
- Oleg Belyakov (IAEA)
160. Comparison of the equivalent uniform dose (EUD) in prostate cancer for target and organ at risk (OARs) between 3D+IMRT and IMRT treatment techniques
Muhammad Aqeel Hussain (Northwest General hospital & Reseacrch Centre)
6/22/17, 10:30 AM
In radiation therapy (RT) of localized prostate cancer, the main organs at risk (OAR) are bladder and rectum. In this study, rectum and bladder doses for 19 patients were analyzed. The treatment plans were generated with the Intensity Modulation Radiation Therapy (IMRT) and 3-Dimensional Conformal RT (3DCRT) + IMRT techniques. CT simulation was performed with full bladder and empty rectum....
Gyöngyi Farkas (Clinical Department of Radiobiology and Oncocytogenetics, Centre of Radiotherapy, National Institute of Oncology)
6/22/17, 10:35 AM
Introduction Although the effect of ionizing radiation in biological systems depends not only on the applied dose, but also on the used energy, dose rate and filters, these parameters are often neglected during radiation therapy. Peripheral blood lymphocytes were irradiated in vitro with a Varian TrueBeam linear accelerator and chromosomal aberrations were analysed in this biological...
239. First conclusions regarding the validation of an automated micronucleus counting microscope based on samples from prostate tumorous patients
Tímea Hülber (Budapest University of Technology and Economics)
6/22/17, 10:40 AM
**Introduction:** As the part of the validation of an automated micronucleus (MN) counting microscope, we tested its performance in the range of low doses. The MN assay makes it possible to determine the quantity of DNA damage as a biomarker of the received dose. For the testing process we examined blood samples from patients with prostate tumour undergoing low dose rate brachytherapy...
247. In silico model of radiotherapy treatment outcome for different fractionation schemes considering dynamic biological processes
Daniella Fabri (Pontificia Universidad Católica de Chile) , Rosario Astaburuaga (Pontificia Universidad Católica de Chile)
6/22/17, 10:45 AM
**Introduction:** Observational clinical studies of radiotherapy (RT) outcome for different fractionation schemes are a very costly and demanding task. Therefore, the development of computational tools that simulate tumour and normal tissue response under scenarios can be enormously useful for trials design. This work presents a model for treatment outcome evaluation of different fractionation...
312. A Delta TCP tool, based on biological parameters of tumor voxels, to quantify effectiveness of different dose distributions in tumor control
Daniella Fabri (Pontificia Universidad Católica de Chile)
6/22/17, 10:50 AM
Introduction ---------------- Tumor control is the principal aim of curative radiotherapy. For the last decades great advances have been achieved on radiotherapy for delivering highly conformal dose distributions allowing for dose escalation to the most resistant areas. In order to adequately develop strategies for the redistribution of dose (or dose boosting), the predicted effectiveness of...
323. Applied radiation biology and radiotherapy coordinated research projects of the International Atomic Energy Agency (IAEA)
Oleg Belyakov (IAEA)
6/22/17, 10:55 AM
The Applied Radiation Biology and Radiotherapy (ARBR) Section of the Division of Human Health at the Department of Nuclear Sciences and Applications of IAEA performs a number of Coordinated Research Projects (CRPs). Radiation oncology research is represented but not limited to: (i) Randomized Phase III Clinical Trial of Stereotactic Body Radiation Therapy Versus Transarterial Chemoembolization...