Nowadays, there are several developments focused on the expanding of the availability of innovative medical radioisotopes. One of them is the use of mass separators, which can extract a desired isotope from a mixture of others of the same element, a task nearly impossible just by means of chemical methods. An electromagnetic mass separator, dedicated for medical isotope production, has been...
Background: Radioimmunoscintigraphy (RIS) has attracted considerable clinical application in tumor detection. Underglycosylated MUC1 antigen is one of the early hallmarks of tumor genesis and is overexpressed in more than 80% of breast cancers. PR81 is a new murine anti-MUC1 monoclonal antibody (mAb). In this study, as the first step, we have developed an efficient indirect labeling method of...
Background: Prostate cancer (PCa) is the second leading cause of cancer deaths for adult men in the Western world. Although radical prostatectomy and local radiotherapy are largely successful for patients with localized cancer, available treatments for metastatic PCa have demonstrated weak curative efficacy. Consequently, new tools to improve the detection of recurrent PCa, and to identify...
