Background
The preparation of 177Lu-peptides for targeted radionuclide therapy requires the use of lutetium-177 from medium to high specific activity (from 400 to 3000 GBq/mg), which cannot be obtained in low flux research nuclear reactors [1,2]. However, the synthesis of 176Lu in the form of injectable nanoparticles functionalized with target-specific peptides, would allow to irradiate in the...
Background / objective:
Demand for nuclear medicines for diagnostic, therapeutic and theranostic use is growing fast, driven by the development of highly effective novel drugs against cancer and life-threatening diseases. Whereas molybdenum-99 is the most commonly used isotope for diagnostic SPECT scans, it is expected that lutetium-177 will be the main workhorse in the coming decades for...
nano technology